Exposure to Aflatoxin M1 through milk consumption in Tehran population, Iran
نویسندگان
چکیده مقاله:
Milk would be contaminated with Aflatoxin M1 (AFM1) if it was obtained from lactating animal which fed with feedstuffs containing Aflatoxin B1 (AFB1). AFM1 is classified as group 2B, possibly carcinogenic to humans and exposure to AFM1 through milk consumption is a public concern. The purpose of this study was to determine the AFM1 exposure through liquid milk consumption for adult consumers in Tehran. Forty-five samples including raw, pasteurized and UHT milk samples were collected from markets in different cities of Tehran province in January and February 2017. The AFM1 was determined by HPLC method after immunoaffinity column clean up. Also, the milk intake was calculated using household budget survey. Finally, the daily intake of AFM1 through milk consumption was estimated using a deterministic approach. From total 45 samples, AFM1 was detected in 36 (80%) samples, although none of the analyzed samples were exceeded Iran legal limit of 0.1 µg/kg. On the basis of the average milk intake, the mean daily exposure to AFM1 was estimated between 0.03 ng/ Kg BW per day (lower bound estimate) and 0.06 ng/ Kg BW per day (upper bound estimate) and the 95th percentile daily exposure was calculated at 0.14 ng/ Kg BW per day. According to these values, it should be expected adults of Tehran population are not exposed to a significant risk of Hepatocarcinoma associated with AFM1 intake through milk consumption.
منابع مشابه
Exposure Assessment of Infants to Aflatoxin M1 through Consumption of Breast Milk and Infant Powdered Milk in Brazil
Aflatoxin M₁ (AFM₁) is an important biomarker that can be used to evaluate aflatoxin exposure in both humans and animals. The aim of this study was to evaluate the exposure degree of infants to AFM₁ through consumption of breast milk and infant powdered milk in Brazil. For this purpose, the estimated daily intake (EDI) for infants was calculated based on the AFM₁ levels analyzed in 94 breast mi...
متن کاملDietary exposure to tetracycline residues through milk consumption in Iran
BACKGROUND The abundant use of tetracycline antibiotics in veterinary medicine may result in the presence of their residues in milk at unsafe concentrations that can adversely affect public health. The aim of the current study was to evaluate the risk of tetracycline residue (TET) intake via milk consumption amongst different age groups of human consumers in Iran. METHODS To quantify the drug...
متن کاملExposure of Infants to Aflatoxin M1 from Mother's Breast Milk in Ilam, Western Iran.
OBJECTIVES Aflatoxins as a highly toxic group of mycotoxins are present in the environment and foodstuff. These have been reported to cause serious health problems in humans. Since aflatoxin M1 (AFM1) is excreted into breast milk, investigating the exposure of infants to AFM1 is of special concern. METHODS In the present study, breast milk samples were collected from 85 lactating mothers in I...
متن کاملInfants’ Exposure to Aflatoxin M1 from Mother’s Breast Milk in Iran
BACKGROUND The occurrence of aflatoxin M1 (AFM1) in milk, especially breast milk, is a valuable biomarker for exposure determination to aflatoxin B(1) (AFB(1)). In the present study, the risk of exposure to AFM(1) in infants fed breast milk was investigated. METHODS An enzyme-linked immunosorbent assay (ELISA) was used for the analysis of AFM(1) in breast milk samples from 132 lactating mothe...
متن کاملAflatoxin M1 Contamination in Pasteurized Milk in Mashhad, Iran
The aim of this study was to evaluate aflatoxin M1 (AFM1) contamination in pasteurized milk samples in Mashhad, Iran. One hundred and ten milk samples from different supermarkets were collected during three months in spring and investigated by Enzyme Linked Immuno Sorbent Assay (ELISA). AFM1 was found in 100% of the milk samples. About 5.4% of the samples c...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 18 شماره 3
صفحات 1332- 1340
تاریخ انتشار 2019-07-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023